FBXO5

Across TCGA patient cohorts, FBXO5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,547 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBXO5-associated genes across cancer lineages are GIPR, PIH1D1, and TLE6. Each is linked with FBXO5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO5-to-partner and partner-to-FBXO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO5 versus GIPR in BRCA, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO5→partner) and Y-score (partner→FBXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GIPR →	-2.595	-1.166	<.001	.003	3	1
BRCA	PIH1D1 →	-0.470	-0.835	.003	.001	3	1
BRCA	TLE6 →	-1.350	-0.918	<.001	.006	3	1
BRCA	BCAT2 →	-1.590	-1.508	<.001	<.001	3	1
BRCA	CWH43 →	+1.605	+1.261	.001	.004	3	1
BRCA	ENOX1 →	-1.692	-1.234	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,547 associations by consensus.

FBXO5 vs GIPR — BRCA

Explore this scatter interactively →