FBXO5

Across TCGA patient cohorts, FBXO5 mutation is significantly associated with the immune_cell of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO5-associated genes across cancer lineages are Erythrocytes, MEP, and MPP. Each is linked with FBXO5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO5-to-partner and partner-to-FBXO5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by FBXO5-low versus FBXO5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO5→partner) and Y-score (partner→FBXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.021	+2.087	.027	.006	3	2
UCEC	MEP →	+0.028	+3.254	.008	.008	3	2
COAD	MPP →	+0.019	+3.140	.019	.006	3	1
COAD	Preadipocytes →	+0.064	+2.754	<.001	.024	3	1
UCEC	CLP →	-0.055	-3.427	.021	.005	3	1
UCEC	Adipocytes →	+0.017	+1.574	.010	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Erythrocytes by FBXO5 expression — UCEC

Explore this box plot interactively →