FBXO5

Across TCGA cell cohorts, FBXO5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,052 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO5-associated GO terms across cancer lineages are Positive regulation of cell cycle, Spindle elongation, and Centrosome duplication. Each is linked with FBXO5 in more than 19 cancer types. Because this analysis shows association rather than direction, both FBXO5-to-partner and partner-to-FBXO5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle grouped by FBXO5-low versus FBXO5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO5→partner) and Y-score (partner→FBXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.086	+1.477	<.001	<.001	3	20
BONE	Spindle elongation →	+0.328	+1.115	.002	.001	3	20
BONE	Centrosome duplication →	+0.118	+0.971	.001	.002	3	20
OESOPHAGUS	Regulation of nuclear division →	+0.156	+1.066	<.001	<.001	3	20
OESOPHAGUS	Regulation of chromosome segregation →	+0.167	+1.146	<.001	<.001	3	20
OESOPHAGUS	DNA-templated DNA replication →	+0.118	+1.033	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,052 associations by consensus.

Positive regulation of cell cycle by FBXO5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →