FBXO45

Across TCGA patient cohorts, FBXO45 mutation is significantly associated with the RNA expression of many other genes, with 757 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO45-associated genes across cancer lineages are LINC02563, IGHD5-12, and NCOA4P1. Each is linked with FBXO45 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO45-to-partner and partner-to-FBXO45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02563 grouped by FBXO45-low versus FBXO45-high in PAAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO45→partner) and Y-score (partner→FBXO45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	LINC02563 →	+0.140	+6.095	.006	.001	3	2
UCEC	IGHD5-12 →	+0.555	+3.538	<.001	.003	3	2
UCEC	NCOA4P1 →	+0.083	+2.239	<.001	.009	3	2
COAD	RNU7-176P →	+0.537	+7.741	<.001	.009	3	1
SKCM	ATP2B2-IT1 →	+0.074	+7.816	<.001	.008	3	1
BRCA	RNA5SP24 →	+0.317	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 757 associations by consensus.

LINC02563 by FBXO45 expression — PAAD

Explore this box plot interactively →