FBXO44

Across TCGA pan-cancer cohorts, FBXO44 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FBXO44 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FBXO44 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FBXO44 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where FBXO44 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	IV	0.123	0.785	.009	30	view →
PDAC	OS	Tertile	All	0.240	0.702	.005	21	view →
HNSC	DFS	Median	All	0.723	0.517	.011	15	view →
GBM	OS	Median	All	0.336	0.691	<.001	11	view →
LUAD	DFS	Tertile	All	1.000	0.572	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FBXO44–CCRCC (OS)

Open the CCRCC breakdown →