FBXO44

Across TCGA cell cohorts, FBXO44 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FBXO44-associated genes across cancer lineages are C1orf87, OR1M1, and OR9A2. Each is linked with FBXO44 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO44-to-partner and partner-to-FBXO44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf87 grouped by FBXO44-low versus FBXO44-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO44→partner) and Y-score (partner→FBXO44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C1orf87 →	+0.056	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR1M1 →	+0.019	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR9A2 →	+0.018	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR5T2 →	+0.006	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	FAM25C →	+0.351	+5.209	<.001	.005	3	1
LARGE_INTESTINE	IL20 →	+0.288	+3.662	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C1orf87 by FBXO44 expression — BLOOD_Lymphoma

Explore this box plot interactively →