FBXO42

Across TCGA cell cohorts, FBXO42 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,247 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO42-associated GO terms across cancer lineages are Regulation of type 2 mitophagy, Autophagosome organization, and Golgi vesicle transport. Each is linked with FBXO42 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXO42-to-partner and partner-to-FBXO42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of type 2 mitophagy grouped by FBXO42-low versus FBXO42-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO42→partner) and Y-score (partner→FBXO42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of type 2 mitophagy →	+0.123	+0.759	<.001	<.001	3	15
STOMACH	Autophagosome organization →	+0.092	+1.022	<.001	<.001	3	14
STOMACH	Golgi vesicle transport →	+0.078	+0.734	<.001	<.001	3	13
LIVER	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.077	+0.550	<.001	.001	3	13
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.070	+0.833	<.001	.002	2	13
LIVER	Organelle transport along microtubule →	+0.067	+0.573	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,247 associations by consensus.

Regulation of type 2 mitophagy by FBXO42 expression — LIVER

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