FBXO40

Across TCGA patient cohorts, FBXO40 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,598 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FBXO40-associated proteins across cancer lineages are DOCK8_S451, HCLS1, and IL16. Each is linked with FBXO40 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO40-to-partner and partner-to-FBXO40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO40 versus DOCK8_S451 in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO40→partner) and Y-score (partner→FBXO40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK8_S451 →	+1.004	+0.105	<.001	<.001	3	6
GBM	HCLS1 →	+0.679	+0.205	<.001	.002	3	6
HNSC	IL16 →	+0.598	+0.808	<.001	.001	3	6
HNSC	PIK3R1 →	+0.211	+0.810	<.001	.003	3	6
GBM	DOCK2 →	+0.600	+0.280	<.001	<.001	3	6
LSCC	FNBP1 →	+0.329	+0.083	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,598 associations by consensus.

FBXO40 vs DOCK8_S451 — LSCC

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