FBXO40

Across TCGA cell cohorts, FBXO40 RNA expression is significantly associated with the go_rna of many other GO terms, with 588 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO40-associated GO terms across cancer lineages are Negative regulation of adenylate cyclase activity, Regulation of triglyceride catabolic process, and Amylin receptor 1 signaling pathway. Each is linked with FBXO40 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXO40-to-partner and partner-to-FBXO40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of adenylate cyclase activity grouped by FBXO40-low versus FBXO40-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO40→partner) and Y-score (partner→FBXO40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of adenylate cyclase activity →	-0.113	-0.002	.002	.002	3	3
LARGE_INTESTINE	Regulation of triglyceride catabolic process →	-0.124	-0.003	.001	.003	3	3
LARGE_INTESTINE	Amylin receptor 1 signaling pathway →	-1.153	-0.003	.005	.005	3	3
LARGE_INTESTINE	Regulation of hemostasis →	-0.096	-0.003	.003	.005	3	3
LARGE_INTESTINE	Negative regulation of hemostasis →	-0.115	-0.003	.001	.003	3	3
BLOOD_Lymphoma	Gonadotropin secretion →	-0.653	-0.029	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 588 associations by consensus.

Negative regulation of adenylate cyclase activity by FBXO40 expression — LARGE_INTESTINE

Explore this box plot interactively →