FBXO39

Across TCGA patient cohorts, FBXO39 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,128 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FBXO39-associated GO terms across cancer lineages are Regulation of viral genome replication, Viral genome replication, and Response to type I interferon. Each is linked with FBXO39 in more than 29 cancer types. Because this analysis shows association rather than direction, both FBXO39-to-partner and partner-to-FBXO39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of viral genome replication grouped by FBXO39-low versus FBXO39-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO39→partner) and Y-score (partner→FBXO39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of viral genome replication →	+0.117	+0.158	<.001	<.001	3	30
SCLC	Viral genome replication →	+0.092	+0.163	<.001	<.001	3	29
SCLC	Response to type I interferon →	+0.085	+0.140	.001	.001	3	28
SCLC	Regulation of viral process →	+0.088	+0.143	<.001	<.001	3	28
SCLC	Antiviral innate immune response →	+0.102	+0.227	.001	<.001	3	27
SCLC	Interferon-mediated signaling pathway →	+0.086	+0.130	<.001	.002	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,128 associations by consensus.

Regulation of viral genome replication by FBXO39 expression — SCLC

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