FBXO39

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FBXO39 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,394 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FBXO39-associated GO terms across cancer lineages are Regulation of protein deubiquitination, Positive regulation of defense response to virus by host, and Regulation of viral process. Each is linked with FBXO39 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBXO39-to-partner and partner-to-FBXO39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein deubiquitination grouped by FBXO39-low versus FBXO39-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO39→partner) and Y-score (partner→FBXO39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTRegulation of protein deubiquitination →+0.115+0.265.003.009312
UPPER_AERODIGESTIVE_TRACTPositive regulation of defense response to virus by host →+0.162+0.856<.001<.001311
BREASTRegulation of viral process →+0.111+0.316<.001.001311
CNSRegulation of response to cytokine stimulus →+0.080+0.598<.001<.001311
URINARY_TRACTPositive regulation of protein deubiquitination →+0.163+0.300<.001.002310
SOFT_TISSUEAntigen processing and presentation of exogenous peptide antigen via MHC class Ib →+0.248+0.348<.001.007310
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,394 associations by consensus.

Regulation of protein deubiquitination by FBXO39 expression — URINARY_TRACT

Box plot of Regulation of protein deubiquitination in FBXO39-low vs FBXO39-high samples in URINARY_TRACT.

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