FBXO36-IT1

Across TCGA pan-cancer cohorts, FBXO36-IT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FBXO36-IT1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher FBXO36-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FBXO36-IT1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCS show a favorable association.

UVM, MESO, and LUAD are the cancer types where FBXO36-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.056	0.870	<.001	108	view →
MESO	OS	Tertile	III,IV	0.036	0.563	<.001	54	view →
LUAD	DFS	Tertile	III,IV	0.455	0.231	.028	24	view →
UCS	OS	Tertile	IV	1.000	0.293	.035	18	view →
GBM	OS	Tertile	All	0.188	0.458	<.001	18	view →
LUSC	OS	Tertile	III,IV	0.054	0.768	<.001	18	view →
HNSC	DFS	Tertile	IV	0.711	0.326	.012	18	view →
TGCT	DFS	Quartile	III,IV	0.505	1.000	.044	12	view →
COAD	OS	Tertile	III,IV	0.403	0.718	.011	12	view →
THCA	DFS	Tertile	IV	0.613	0.904	.015	12	view →
SARC	OS	Tertile	All	1.000	0.461	.030	12	view →
PRAD	DFS	Tertile	All	0.985	0.926	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FBXO36-IT1–UVM (OS)

Open the UVM breakdown →