FBXO34

Across TCGA patient cohorts, FBXO34 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,650 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FBXO34-associated proteins across cancer lineages are PPM1A, PPP2R5E, and PPP4R3A. Each is linked with FBXO34 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO34-to-partner and partner-to-FBXO34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO34 versus PPM1A in LUAD, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO34→partner) and Y-score (partner→FBXO34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPM1A →	+0.221	+0.495	<.001	<.001	3	6
GBM	PPP2R5E →	+0.284	+0.279	<.001	<.001	3	6
GBM	PPP4R3A →	+0.309	+0.311	<.001	.001	3	6
LUAD	RPS6KA5 →	+0.411	+0.354	.003	.009	3	6
GBM	YLPM1 →	+0.276	+0.261	<.001	<.001	3	6
CCRCC	CKAP4_S26 →	-1.054	-0.632	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,650 associations by consensus.

FBXO34 vs PPM1A — LUAD

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