FBXO34

Across TCGA cell cohorts, FBXO34 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,013 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO34-associated GO terms across cancer lineages are Endosome to lysosome transport, Regulation of alternative mRNA splicing, via spliceosome, and miRNA processing. Each is linked with FBXO34 in more than 13 cancer types. Because this analysis shows association rather than direction, both FBXO34-to-partner and partner-to-FBXO34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome to lysosome transport grouped by FBXO34-low versus FBXO34-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO34→partner) and Y-score (partner→FBXO34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endosome to lysosome transport →	+0.065	+0.641	<.001	.001	3	14
OESOPHAGUS	Regulation of alternative mRNA splicing, via spliceosome →	+0.090	+0.788	.001	.001	3	13
BREAST	miRNA processing →	+0.079	+0.668	.002	.005	2	13
BREAST	Regulation of protein localization to nucleus →	+0.073	+0.692	.004	.001	3	12
OESOPHAGUS	Post-transcriptional gene silencing →	+0.097	+0.745	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to nucleus →	+0.092	+0.681	<.001	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,013 associations by consensus.

Endosome to lysosome transport by FBXO34 expression — STOMACH

Explore this box plot interactively →