FBXO31

Across TCGA patient cohorts, FBXO31 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,982 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO31-associated proteins across cancer lineages are TERF2, TERF2IP, and FTO. Each is linked with FBXO31 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO31-to-partner and partner-to-FBXO31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO31 versus TERF2 in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO31→partner) and Y-score (partner→FBXO31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TERF2 →	+0.318	+0.360	.007	<.001	2	6
OV	TERF2IP →	+0.303	+0.506	<.001	<.001	3	5
OV	FTO →	+0.305	+0.409	.002	.007	3	4
OV	HSDL1 →	+0.496	+0.561	<.001	<.001	3	4
LUAD	AP1G2 →	-0.275	-0.467	.001	<.001	3	4
OV	DHX38 →	+0.253	+0.426	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,982 associations by consensus.

FBXO31 vs TERF2 — GBM

Explore this scatter interactively →