FBXO30

Across TCGA patient cohorts, FBXO30 protein abundance is significantly associated with the RNA expression of many other genes, with 10,364 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO30-associated genes across cancer lineages are HDAC2, UST, and EPM2A. Each is linked with FBXO30 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO30-to-partner and partner-to-FBXO30 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO30 versus HDAC2 in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO30→partner) and Y-score (partner→FBXO30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HDAC2 →	+0.625	+0.233	<.001	<.001	3	6
UCEC	UST →	+0.946	+0.200	<.001	.001	3	5
GBM	EPM2A →	+0.472	+0.262	<.001	<.001	3	5
LSCC	GNB4 →	+0.752	+0.231	<.001	.001	3	5
BRCA	PCMT1 →	+0.527	+0.285	.002	<.001	3	5
COAD	HSF2 →	+0.452	+0.169	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,364 associations by consensus.

FBXO30 vs HDAC2 — LSCC

Explore this scatter interactively →