FBXO30

Across TCGA cell cohorts, FBXO30 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO30-associated GO terms across cancer lineages are Termination of RNA polymerase II transcription, DNA alkylation repair, and Protein localization to nucleus. Each is linked with FBXO30 in more than 12 cancer types. Because this analysis shows association rather than direction, both FBXO30-to-partner and partner-to-FBXO30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Termination of RNA polymerase II transcription grouped by FBXO30-low versus FBXO30-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO30→partner) and Y-score (partner→FBXO30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Termination of RNA polymerase II transcription →	+0.108	+0.770	<.001	<.001	3	12
LUNG_NSCLC_LUAD	DNA alkylation repair →	+0.103	+0.736	<.001	<.001	3	12
BREAST	Protein localization to nucleus →	+0.061	+0.678	<.001	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.044	+0.594	.002	.001	3	12
URINARY_TRACT	Ribosomal small subunit export from nucleus →	+0.118	+0.885	.009	.003	1	13
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.073	+0.695	.003	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Termination of RNA polymerase II transcription by FBXO30 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →