FBXO30

Across TCGA cell cohorts, FBXO30 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO30-associated genes across cancer lineages are FTMT, MMP8, and MAGEB4. Each is linked with FBXO30 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO30-to-partner and partner-to-FBXO30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by FBXO30-low versus FBXO30-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO30→partner) and Y-score (partner→FBXO30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
LARGE_INTESTINE	MMP8 →	+0.121	+3.464	<.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1
STOMACH	SIGLEC9 →	+0.434	+3.637	.002	.008	3	1
STOMACH	CMTM5 →	+0.041	+3.830	<.001	.005	3	1
STOMACH	HTR3C →	+0.059	+3.632	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

FTMT by FBXO30 expression — SOFT_TISSUE

Explore this box plot interactively →