FBXO30-DT

Across TCGA pan-cancer cohorts, FBXO30-DT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated FBXO30-DT data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FBXO30-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated FBXO30-DT expression acts as an unfavorable survival marker, although some lineages such as ACC and SKCM show a favorable association.

ACC, SKCM, and HNSC are the cancer types where FBXO30-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.722	0.379	<.001	81	view →
SKCM	DFS	Median	All	0.685	0.551	<.001	74	view →
HNSC	DFS	Median	IV	0.415	0.241	<.001	45	view →
KIRP	DFS	Median	II,III,IV	0.895	0.247	.001	40	view →
BLCA	DFS	Tertile	All	0.174	0.523	.002	32	view →
LGG	DFS	Tertile	All	0.893	0.766	<.001	28	view →
CHOL	DFS	Median	All	0.729	0.121	.002	25	view →
CESC	OS	Tertile	IV	0.785	0.182	<.001	24	view →
READ	OS	Quartile	IV	1.000	0.319	.003	23	view →
LIHC	OS	Tertile	III,IV	0.709	0.467	.013	19	view →
MESO	DFS	Tertile	IV	0.717	0.226	.001	18	view →
PAAD	DFS	Quartile	All	0.576	0.373	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

FBXO30-DT–ACC (OS)

Open the ACC breakdown →