FBXO24

Across TCGA pan-cancer cohorts, FBXO24 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FBXO24 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FBXO24 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FBXO24 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where FBXO24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.994	0.702	.001	20	view →
CCRCC	DFS	Tertile	All	0.887	0.307	.010	15	view →
HNSC	OS	Median	II,III,IV	1.000	0.785	.019	7	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FBXO24–LUAD (DFS)

Open the LUAD breakdown →