FBXO24

Across TCGA patient cohorts, FBXO24 mutation is significantly associated with the RNA expression of many other genes, with 2,821 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO24-associated genes across cancer lineages are RN7SL447P, LINC02438, and NBEAP3. Each is linked with FBXO24 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXO24-to-partner and partner-to-FBXO24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by FBXO24-low versus FBXO24-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO24→partner) and Y-score (partner→FBXO24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL447P →	+0.223	+5.786	<.001	<.001	3	3
UCEC	LINC02438 →	+0.487	+2.024	<.001	.001	3	3
COAD	NBEAP3 →	+0.027	+4.418	<.001	.008	3	3
SKCM	RNU4-59P →	+0.068	+2.284	<.001	.008	3	3
LGG	HMGB3P20 →	+0.069	+5.093	<.001	.008	3	3
CESC	RN7SL543P →	+0.129	+4.760	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,821 associations by consensus.

RN7SL447P by FBXO24 expression — CESC

Explore this box plot interactively →