FBXO24

Across TCGA cell cohorts, FBXO24 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO24-associated genes across cancer lineages are IFNA14, C22orf42, and SLC10A2. Each is linked with FBXO24 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO24-to-partner and partner-to-FBXO24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA14 grouped by FBXO24-low versus FBXO24-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO24→partner) and Y-score (partner→FBXO24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IFNA14 →	+0.036	+5.781	<.001	.001	3	2
LARGE_INTESTINE	C22orf42 →	+0.025	+3.232	<.001	<.001	3	2
SKIN	SLC10A2 →	+0.002	+3.700	<.001	.009	3	1
SKIN	ARMC3 →	+0.114	+3.478	.006	.005	3	1
SKIN	MMP26 →	+0.011	+3.700	<.001	.009	3	1
SKIN	TPPP2 →	+0.043	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

IFNA14 by FBXO24 expression — BREAST

Explore this box plot interactively →