FBXO22

Across TCGA patient cohorts, FBXO22 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,965 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO22-associated proteins across cancer lineages are EDC3, RCN2, and RTF1. Each is linked with FBXO22 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO22-to-partner and partner-to-FBXO22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO22 versus EDC3 in COAD, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO22→partner) and Y-score (partner→FBXO22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EDC3 →	+0.275	+0.454	<.001	.003	3	6
OV	RCN2 →	+0.372	+0.454	.005	<.001	3	6
GBM	RTF1 →	+0.311	+0.390	.002	.001	3	6
OV	ANP32A →	+0.752	+0.444	<.001	.001	3	6
GBM	TRIM28 →	+0.415	+0.504	<.001	<.001	3	5
LSCC	PAF1 →	+0.259	+0.410	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,965 associations by consensus.

FBXO22 vs EDC3 — COAD

Explore this scatter interactively →