FBXO22

Across TCGA patient cohorts, FBXO22 protein abundance is significantly associated with the RNA expression of many other genes, with 12,634 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FBXO22-associated genes across cancer lineages are IMP3, MESD, and CAMLG. Each is linked with FBXO22 in more than 7 cancer types. Because this analysis shows association rather than direction, both FBXO22-to-partner and partner-to-FBXO22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO22 versus IMP3 in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO22→partner) and Y-score (partner→FBXO22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IMP3 →	+0.594	+0.246	.009	<.001	3	8
UCEC	MESD →	+0.626	+0.365	.001	<.001	3	7
OV	CAMLG →	+0.730	+0.316	<.001	.002	3	6
COAD	RPS27L →	+0.855	+0.300	<.001	<.001	3	6
OV	SCAPER →	+0.517	+0.308	.006	.003	3	5
HNSC	SNUPN →	+0.531	+0.170	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,634 associations by consensus.

FBXO22 vs IMP3 — UCEC

Explore this scatter interactively →