FBXO22

Across TCGA cell cohorts, FBXO22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,445 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FBXO22-associated GO terms across cancer lineages are Regulation of skeletal muscle fiber development, Metaphase/anaphase transition of mitotic cell cycle, and snRNA transport. Each is linked with FBXO22 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXO22-to-partner and partner-to-FBXO22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of skeletal muscle fiber development grouped by FBXO22-low versus FBXO22-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO22→partner) and Y-score (partner→FBXO22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of skeletal muscle fiber development →	+0.266	+0.708	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Metaphase/anaphase transition of mitotic cell cycle →	+0.116	+0.847	.006	.005	3	10
SOFT_TISSUE	snRNA transport →	+0.106	+0.787	<.001	<.001	3	9
SKIN	Positive regulation of pentose-phosphate shunt →	+0.147	+0.524	<.001	<.001	3	9
SKIN	Leukocyte mediated immunity →	-0.057	-0.648	.001	<.001	3	9
SOFT_TISSUE	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.078	+0.845	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,445 associations by consensus.

Regulation of skeletal muscle fiber development by FBXO22 expression — BREAST

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