FBXO21

Across TCGA patient cohorts, FBXO21 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,106 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO21-associated proteins across cancer lineages are SART3, DOK3, and FERMT3. Each is linked with FBXO21 in more than 6 cancer types. Because this analysis shows association rather than direction, both FBXO21-to-partner and partner-to-FBXO21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO21 versus SART3 in LSCC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO21→partner) and Y-score (partner→FBXO21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SART3 →	+0.318	+0.619	<.001	<.001	3	7
LSCC	DOK3 →	-0.452	-0.632	<.001	<.001	3	7
GBM	FERMT3 →	-0.431	-0.334	<.001	<.001	3	7
BRCA	PLEK →	-0.476	-0.454	.001	.002	3	7
LSCC	FMNL1 →	-0.517	-0.487	<.001	<.001	3	7
LSCC	THEMIS2 →	-0.460	-0.609	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,106 associations by consensus.

FBXO21 vs SART3 — LSCC

Explore this scatter interactively →