FBXO17

Across TCGA cell cohorts, FBXO17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,590 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FBXO17-associated GO terms across cancer lineages are Regulation of regulated secretory pathway, Establishment of RNA localization, and GMP biosynthetic process. Each is linked with FBXO17 in more than 9 cancer types. Because this analysis shows association rather than direction, both FBXO17-to-partner and partner-to-FBXO17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of regulated secretory pathway grouped by FBXO17-low versus FBXO17-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO17→partner) and Y-score (partner→FBXO17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of regulated secretory pathway →	-0.058	-2.350	<.001	<.001	3	10
OESOPHAGUS	Establishment of RNA localization →	+0.127	+2.663	.001	.007	3	10
PANCREAS	GMP biosynthetic process →	+0.164	+2.823	<.001	<.001	3	10
OESOPHAGUS	RNA localization →	+0.118	+3.341	.001	<.001	3	10
PANCREAS	Cytoplasmic translational initiation →	+0.071	+2.495	.002	<.001	3	10
LUNG_SCLC	Positive regulation of potassium ion import across plasma membrane →	-0.177	-2.301	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,590 associations by consensus.

Regulation of regulated secretory pathway by FBXO17 expression — STOMACH

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