Across TCGA patient cohorts, FBXO16 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO16-associated genes across cancer lineages are p62 Lck ligand, STAT3_pY705, and Cyclin-B1. Each is linked with FBXO16 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO16-to-partner and partner-to-FBXO16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO16→partner) and Y-score (partner→FBXO16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.522	+2.331	<.001	.019	3	1
UCEC	STAT3_pY705 →	-0.385	-3.169	.002	.018	3	1
UCEC	Cyclin-B1 →	+0.626	+3.584	.021	.002	3	1
UCEC	FASN →	+0.486	+3.000	.010	.036	2	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.577	+2.817	.018	.036	2	1
UCEC	MEK1 →	+0.557	+3.321	.001	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

FBXO16 survival (RNA) · tumor vs normal (RNA) · all FBXO16 data types