FBXO15

Across TCGA cell cohorts, FBXO15 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO15-associated genes across cancer lineages are OR5V1, NXF5, and RFPL3. Each is linked with FBXO15 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO15-to-partner and partner-to-FBXO15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5V1 grouped by FBXO15-low versus FBXO15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO15→partner) and Y-score (partner→FBXO15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR5V1 →	+0.010	+5.022	<.001	.002	3	2
LARGE_INTESTINE	NXF5 →	+0.032	+4.467	<.001	.004	3	1
LARGE_INTESTINE	RFPL3 →	+0.045	+4.095	<.001	.009	3	1
LARGE_INTESTINE	KRTAP10-1 →	+0.009	+4.415	<.001	.007	3	1
SKIN	INSL5 →	+0.048	+4.467	.001	.004	3	1
SKIN	KRTAP2-4 →	+0.036	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR5V1 by FBXO15 expression — LARGE_INTESTINE

Explore this box plot interactively →