FBXO11

Across TCGA patient cohorts, FBXO11 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,129 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO11-associated proteins across cancer lineages are HDAC2, PUM2, and TRRAP. Each is linked with FBXO11 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO11 versus HDAC2 in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HDAC2 →	+0.330	+0.437	<.001	.001	3	6
HNSC	PUM2 →	+0.215	+0.373	<.001	.001	3	5
HNSC	TRRAP →	+0.215	+0.397	<.001	.002	3	5
LSCC	XPO1 →	+0.259	+0.449	<.001	<.001	3	5
LSCC	PPIG →	+0.277	+0.381	<.001	<.001	3	5
GBM	SNRPD2 →	+0.316	+0.394	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,129 associations by consensus.

FBXO11 vs HDAC2 — HNSC

Explore this scatter interactively →