FBXO11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FBXO11 protein abundance is significantly associated with the RNA expression of many other genes, with 9,492 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO11-associated genes across cancer lineages are EME1, TFAP4, and LYRM4. Each is linked with FBXO11 in more than 3 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO11 versus EME1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEME1 →+0.852+0.217<.001.00734
GBMTFAP4 →+0.388+0.184<.001<.00134
LSCCLYRM4 →+0.672+0.244<.001<.00134
LSCCECT2 →+0.975+0.267<.001<.00133
LSCCCOQ3 →+0.674+0.192<.001.00133
UCECKIF23 →+0.985+0.245<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,492 associations by consensus.

FBXO11 vs EME1 — UCEC

Per-sample scatter of FBXO11 vs EME1 in UCEC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration