FBXO11

Across TCGA patient cohorts, FBXO11 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,333 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO11-associated proteins across cancer lineages are SF3B6, SMC1A, and SMC3. Each is linked with FBXO11 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO11 versus SF3B6 in GBM, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B6 →	+0.382	+0.273	<.001	<.001	3	5
LSCC	SMC1A →	+0.252	+0.225	<.001	<.001	3	5
GBM	SMC3 →	+0.221	+0.159	<.001	<.001	3	5
UCEC	NSMCE2 →	+0.306	+0.311	<.001	<.001	3	5
UCEC	NUP153 →	+0.291	+0.296	<.001	<.001	3	5
GBM	CBX3 →	+0.480	+0.222	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,333 associations by consensus.

FBXO11 vs SF3B6 — GBM

Explore this scatter interactively →