FBXO11

Across TCGA patient cohorts, FBXO11 mutation is significantly associated with the RNA expression of many other genes, with 836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO11-associated genes across cancer lineages are RPS29P13, HNRNPA3P16, and CDH18-AS1. Each is linked with FBXO11 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P13 grouped by FBXO11-low versus FBXO11-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	RPS29P13 →	+0.284	+7.962	<.001	.007	3	3
SKCM	HNRNPA3P16 →	+0.044	+2.915	<.001	.008	3	3
THCA	CDH18-AS1 →	+0.084	+7.962	<.001	.007	3	2
CESC	RNA5SP394 →	+0.258	+3.760	<.001	.004	3	2
BLCA	A2ML1-AS1 →	+0.311	+4.326	<.001	.001	3	2
BLCA	ENO1P2 →	+0.040	+3.577	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 836 associations by consensus.

RPS29P13 by FBXO11 expression — THCA

Explore this box plot interactively →