FBXO11

Across TCGA cell cohorts, FBXO11 RNA expression is significantly associated with the RNA expression of many other genes, with 10,823 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible FBXO11-associated genes across cancer lineages are PPP4R3B, SPAST, and PUM2. Each is linked with FBXO11 in more than 19 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO11 versus PPP4R3B in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PPP4R3B →	+1.095	+1.351	<.001	<.001	3	20
OESOPHAGUS	SPAST →	+1.333	+1.001	<.001	.003	3	19
OESOPHAGUS	PUM2 →	+1.238	+1.178	<.001	<.001	3	19
LUNG_NSCLC_LUSC	USP34 →	+1.188	+1.156	<.001	<.001	3	19
LUNG_NSCLC_LUSC	PAPOLG →	+1.060	+0.984	.001	.001	3	18
OESOPHAGUS	SOS1 →	+1.141	+1.113	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,823 associations by consensus.

FBXO11 vs PPP4R3B — LUNG_NSCLC_LUSC

Explore this scatter interactively →