FBXO11

Across TCGA cell cohorts, FBXO11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,182 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FBXO11-associated GO terms across cancer lineages are Heterochromatin organization, Regulation of nucleotide-excision repair, and Heterochromatin formation. Each is linked with FBXO11 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by FBXO11-low versus FBXO11-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin organization →	+0.064	+0.552	<.001	<.001	3	15
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.112	+0.986	<.001	<.001	3	14
LARGE_INTESTINE	Heterochromatin formation →	+0.069	+0.762	<.001	<.001	3	14
STOMACH	Negative regulation of gene expression, epigenetic →	+0.068	+0.550	<.001	<.001	3	14
STOMACH	mRNA destabilization →	+0.065	+0.879	<.001	<.001	3	13
LARGE_INTESTINE	Positive regulation of DNA repair →	+0.064	+0.734	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,182 associations by consensus.

Heterochromatin organization by FBXO11 expression — OVARY

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