FBXO11

Across TCGA cell cohorts, FBXO11 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO11-associated genes across cancer lineages are CRT0105446, Serdemetan, and I-BET-151. Each is linked with FBXO11 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO11-to-partner and partner-to-FBXO11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRT0105446 grouped by FBXO11-low versus FBXO11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO11→partner) and Y-score (partner→FBXO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CRT0105446 →	+0.470	+2.874	.010	.021	3	1
LARGE_INTESTINE	Serdemetan →	+0.351	+3.125	.015	.008	3	1
LARGE_INTESTINE	I-BET-151 →	+0.463	+3.000	.022	.017	3	1
LARGE_INTESTINE	50869 →	+0.401	+2.678	.036	.037	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.649	+2.807	.028	.032	3	1
LARGE_INTESTINE	GSK319347A →	+0.240	+2.321	.013	.047	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CRT0105446 by FBXO11 expression — LARGE_INTESTINE

Explore this box plot interactively →