Across TCGA patient cohorts, FBXL7 protein abundance is significantly associated with the RNA expression of many other genes, with 5,057 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXL7-associated genes across cancer lineages are NAV3, PLSCR4, and CNRIP1. Each is linked with FBXL7 in more than 3 cancer types. Because this analysis shows association rather than direction, both FBXL7-to-partner and partner-to-FBXL7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL7→partner) and Y-score (partner→FBXL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NAV3 →	+1.513	+0.652	.002	<.001	3	4
BRCA	PLSCR4 →	+1.188	+0.527	<.001	<.001	3	3
OV	CNRIP1 →	+1.252	+0.698	.007	.008	3	3
OV	RHOJ →	+1.107	+0.573	<.001	.002	3	3
BRCA	AOX1 →	+1.084	+0.503	<.001	.001	3	3
OV	ZEB1 →	+1.319	+0.435	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,057 associations by consensus.

Exploration

FBXL7 survival (RNA) · tumor vs normal (RNA) · all FBXL7 data types