Across TCGA cell cohorts, FBXL7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,973 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FBXL7-associated GO terms across cancer lineages are Regulation of mucus secretion, Regulation of cardiac muscle contraction, and Negative regulation of lysosome organization. Each is linked with FBXL7 in more than 6 cancer types. Because this analysis shows association rather than direction, both FBXL7-to-partner and partner-to-FBXL7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL7→partner) and Y-score (partner→FBXL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of mucus secretion →	-0.878	-1.254	.009	.006	3	7
LUNG_NSCLC_LUAD	Regulation of cardiac muscle contraction →	-0.072	-0.742	<.001	.008	3	7
CNS	Negative regulation of lysosome organization →	+0.056	+0.959	.001	<.001	3	6
SKIN	Positive regulation of sodium ion transport →	-0.156	-1.907	.002	<.001	3	6
OVARY	Positive regulation of sodium ion transmembrane transport →	-0.163	-0.770	.002	.008	3	6
OVARY	Regulation of tyrosine phosphorylation of STAT protein →	-0.146	-1.413	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,973 associations by consensus.

Exploration

FBXL7 survival (RNA) · tumor vs normal (RNA) · all FBXL7 data types