Across TCGA patient cohorts, FBXL6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,496 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXL6-associated proteins across cancer lineages are SCRIB, BOP1, and HGH1. Each is linked with FBXL6 in more than 6 cancer types. Because this analysis shows association rather than direction, both FBXL6-to-partner and partner-to-FBXL6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL6→partner) and Y-score (partner→FBXL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCRIB →	+0.460	+0.773	<.001	<.001	3	7
BRCA	BOP1 →	+0.380	+0.913	<.001	<.001	3	6
OV	HGH1 →	+0.326	+0.923	<.001	<.001	3	6
LSCC	PYCR3 →	+0.495	+0.707	<.001	<.001	3	5
BRCA	THEM6 →	+0.640	+0.891	<.001	<.001	3	5
BRCA	POP1 →	+0.331	+0.922	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,496 associations by consensus.

Exploration

FBXL6 survival (RNA) · tumor vs normal (RNA) · all FBXL6 data types