Across TCGA patient cohorts, FBXL6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,080 significant associations in total. OV shows the largest number of these associations.

The most reproducible FBXL6-associated genes across cancer lineages are GFUS, CYC1, and PYCR3. Each is linked with FBXL6 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXL6-to-partner and partner-to-FBXL6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL6→partner) and Y-score (partner→FBXL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GFUS →	+1.150	+0.419	<.001	<.001	3	5
OV	CYC1 →	+0.904	+0.523	<.001	.002	3	5
OV	PYCR3 →	+0.944	+0.684	<.001	<.001	3	3
OV	RPL8 →	+0.640	+0.453	<.001	.004	3	3
COAD	MFSD3 →	+1.164	+0.730	.005	.006	3	3
OV	MRPL13 →	+0.873	+0.497	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,080 associations by consensus.

Exploration

FBXL6 survival (RNA) · tumor vs normal (RNA) · all FBXL6 data types