Across TCGA cell cohorts, FBXL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,082 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FBXL6-associated GO terms across cancer lineages are Protein linear polyubiquitination, Actomyosin contractile ring organization, and DNA replication proofreading. Each is linked with FBXL6 in more than 13 cancer types. Because this analysis shows association rather than direction, both FBXL6-to-partner and partner-to-FBXL6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL6→partner) and Y-score (partner→FBXL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein linear polyubiquitination →	+0.163	+0.989	<.001	.001	3	14
URINARY_TRACT	Actomyosin contractile ring organization →	+0.199	+1.164	<.001	.002	3	12
BONE	DNA replication proofreading →	+0.275	+1.491	<.001	<.001	3	11
BONE	Cytoplasm protein quality control →	+0.165	+1.223	<.001	<.001	3	10
BONE	Pre-mRNA catabolic process →	+0.267	+1.323	<.001	<.001	3	10
SOFT_TISSUE	Telomere organization →	+0.064	+0.705	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,082 associations by consensus.

Exploration

FBXL6 survival (RNA) · tumor vs normal (RNA) · all FBXL6 data types