FBXL5

Across TCGA cell cohorts, FBXL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXL5-associated GO terms across cancer lineages are Positive regulation of bone development, Cell division, and Nucleotide-excision repair. Each is linked with FBXL5 in more than 12 cancer types. Because this analysis shows association rather than direction, both FBXL5-to-partner and partner-to-FBXL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of bone development grouped by FBXL5-low versus FBXL5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL5→partner) and Y-score (partner→FBXL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of bone development →	+1.220	+0.830	<.001	.001	3	13
BREAST	Cell division →	+0.072	+0.863	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.061	+0.885	.002	<.001	3	11
BREAST	Protein K11-linked ubiquitination →	+0.064	+0.907	.003	<.001	3	11
BREAST	Mitotic cytokinesis →	+0.094	+1.048	<.001	<.001	3	10
SKIN	Regulation of hippo signaling →	+0.073	+0.518	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,695 associations by consensus.

Positive regulation of bone development by FBXL5 expression — STOMACH

Explore this box plot interactively →