FBXL4

Across TCGA cell cohorts, FBXL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,365 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXL4-associated GO terms across cancer lineages are 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process, Golgi organization, and Negative regulation of mitophagy. Each is linked with FBXL4 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXL4-to-partner and partner-to-FBXL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process grouped by FBXL4-low versus FBXL4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL4→partner) and Y-score (partner→FBXL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.115	+0.769	.002	.002	3	15
SOFT_TISSUE	Golgi organization →	+0.061	+0.738	<.001	<.001	3	13
LUNG_SCLC	Negative regulation of mitophagy →	+0.128	+0.861	<.001	<.001	3	13
LUNG_SCLC	Negative regulation of autophagy of mitochondrion →	+0.128	+0.861	<.001	<.001	3	13
STOMACH	Peptidyl-serine modification →	+0.080	+0.567	.001	.005	3	12
BLOOD_Lymphoma	Hair follicle placode formation →	+0.080	+0.661	.008	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,365 associations by consensus.

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process by FBXL4 expression — STOMACH

Explore this box plot interactively →