FBXL21P

Across TCGA pan-cancer cohorts, FBXL21P Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FBXL21P data layer compared with 21 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FBXL21P Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FBXL21P expression acts as an unfavorable survival marker.

LUAD, SCLC, and UCEC are the cancer types where FBXL21P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.178	0.721	.008	14	view →
SCLC	OS	Median	All	0.055	0.708	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FBXL21P–LUAD (DFS)

Open the LUAD breakdown →