FBXL20

Across TCGA patient cohorts, FBXL20 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,487 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXL20-associated proteins across cancer lineages are RHOT1, WDR5, and YTHDC1. Each is linked with FBXL20 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXL20-to-partner and partner-to-FBXL20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL20 versus RHOT1 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL20→partner) and Y-score (partner→FBXL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RHOT1 →	+0.245	+0.720	<.001	.001	3	6
LSCC	WDR5 →	+0.298	+0.564	<.001	<.001	3	5
GBM	YTHDC1 →	+0.272	+0.367	<.001	<.001	3	5
LSCC	MED1 →	+0.278	+0.717	<.001	<.001	3	5
GBM	HDAC2 →	+0.404	+0.489	<.001	<.001	3	5
GBM	STAG2 →	+0.285	+0.324	.004	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,487 associations by consensus.

FBXL20 vs RHOT1 — HNSC

Explore this scatter interactively →