FBXL20

Across TCGA patient cohorts, FBXL20 mutation is significantly associated with the RNA expression of many other genes, with 950 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXL20-associated genes across cancer lineages are LINC01696, MIR7702, and OR7E18P. Each is linked with FBXL20 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXL20-to-partner and partner-to-FBXL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01696 grouped by FBXL20-low versus FBXL20-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL20→partner) and Y-score (partner→FBXL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	LINC01696 →	+0.074	+7.962	<.001	.007	3	2
UCEC	MIR7702 →	+0.163	+3.738	<.001	.009	3	2
CESC	OR7E18P →	+0.030	+4.757	<.001	.004	3	2
SKCM	MTCO1P23 →	+0.029	+2.978	.001	.007	3	2
UCEC	HARBI1 →	+0.311	+2.212	.009	.001	3	2
UCEC	MAFG →	+0.581	+2.180	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 950 associations by consensus.

LINC01696 by FBXL20 expression — THCA

Explore this box plot interactively →