FBXL20

Across TCGA cell cohorts, FBXL20 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXL20-associated genes across cancer lineages are TEKT1, ZNF705D, and AVP. Each is linked with FBXL20 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXL20-to-partner and partner-to-FBXL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEKT1 grouped by FBXL20-low versus FBXL20-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL20→partner) and Y-score (partner→FBXL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	TEKT1 →	+0.063	+4.807	<.001	.006	3	1
BLOOD_Myeloma	ZNF705D →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	CABP5 →	+0.016	+4.867	<.001	.009	3	1
LARGE_INTESTINE	DBX2 →	+0.023	+4.977	<.001	.007	3	1
LARGE_INTESTINE	KRTAP10-1 →	+0.013	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TEKT1 by FBXL20 expression — BLOOD_Myeloma

Explore this box plot interactively →