FBXL2

Across TCGA patient cohorts, FBXL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,280 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FBXL2-associated proteins across cancer lineages are THBS2, TIMP2, and MMP11. Each is linked with FBXL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXL2-to-partner and partner-to-FBXL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL2 versus THBS2 in COAD, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL2→partner) and Y-score (partner→FBXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	THBS2 →	+0.998	+0.504	<.001	<.001	3	5
BRCA	TIMP2 →	+0.553	+0.583	.001	<.001	3	5
LSCC	MMP11 →	+0.714	+0.422	<.001	<.001	3	5
COAD	DBN1 →	+0.343	+0.554	.001	.002	3	5
UCEC	ARMC9 →	+0.371	+0.768	<.001	<.001	3	4
BRCA	SULF1 →	+0.791	+0.578	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,280 associations by consensus.

FBXL2 vs THBS2 — COAD

Explore this scatter interactively →