FBXL19-AS1

Across TCGA pan-cancer cohorts, FBXL19-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of FBXL19-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FBXL19-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FBXL19-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, HNSC, and KIRP are the cancer types where FBXL19-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FBXL19-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	+0.675	<.001	10	view →
HNSC	All	II,III,IV	+0.343	<.001	10	view →
KIRP	All	II,III,IV	+0.985	<.001	9	view →
LIHC	Female	All	+0.590	<.001	9	view →
LUAD	All	All	+0.484	<.001	8	view →
STAD	All	II,III,IV	+0.787	<.001	6	view →
BRCA	All	All	+0.701	<.001	6	view →
UCEC	All	All	+0.591	.001	6	view →
CHOL	All	All	+2.023	<.001	5	view →
BLCA	All	All	+0.547	.005	5	view →
PRAD	All	All	+0.829	<.001	2	view →
ESCA	All	All	+0.782	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

FBXL19-AS1–COAD

Open the COAD breakdown →