FBXL16

Across TCGA cell cohorts, FBXL16 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,682 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FBXL16-associated GO terms across cancer lineages are Primary alcohol biosynthetic process, Negative regulation of cholesterol efflux, and Purine nucleoside triphosphate biosynthetic process. Each is linked with FBXL16 in more than 10 cancer types. Because this analysis shows association rather than direction, both FBXL16-to-partner and partner-to-FBXL16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol biosynthetic process grouped by FBXL16-low versus FBXL16-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL16→partner) and Y-score (partner→FBXL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Primary alcohol biosynthetic process →	-0.267	-1.410	<.001	.001	3	11
KIDNEY	Negative regulation of cholesterol efflux →	+0.303	+2.264	<.001	<.001	3	10
BONE	Purine nucleoside triphosphate biosynthetic process →	+0.130	+2.106	<.001	<.001	3	9
BONE	Purine ribonucleoside triphosphate biosynthetic process →	+0.130	+2.106	<.001	<.001	3	9
LUNG_SCLC	Aldehyde catabolic process →	+0.165	+1.960	.003	.001	3	8
LUNG_SCLC	Tertiary alcohol biosynthetic process →	+1.116	+1.296	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,682 associations by consensus.

Primary alcohol biosynthetic process by FBXL16 expression — LUNG_SCLC

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